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Paula's Choice RESIST Cellular Defense Daily Moisturizer SPF 25 Review

Recently I decided to give the Paula’s Choice moisturizers with SPF another try. I picked up the RESIST Cellular Defense Daily Moisturizer SPF 25.

While I typically prefer my daytime moisturizer to be between 35-50, I know a lot of that is paranoia on my part. SPF 15 filters out 93% of UVB rays, SPF 30 filters out 97% and SPF 50 filters out 98%. So really SPF25 is adequate protection, even if I feel better seeing a higher number.

About Paula’s Choice RESIST Cellular Defense Daily Moisturizer SPF 25
This ultra-gentle yet effective formula has a lightweight, silky-cream texture that hydrates and enhances radiance while providing extremely effective mineral-based, broad-spectrum sun protection. It includes potent antioxidants to defend your skin from environmental stressors, allowing the skin to repair itself on a cellular level, and restoring skin’s ability to resist further signs of aging. Used daily, this moisturizer will help reduce wrinkles and brown spots, while rebuilding collagen and improving skin tone.

  • Fragrance free
  • Colorant free
  • Cruelty free

$27 for 2 oz

Paula’s Choice, Dermstore, B-Glowing

Active Ingredients: Titanium Dioxide 8%; Other Ingredients: Active Ingredients: Titanium Dioxide 8%; Other Ingredients: Water, Tribehenin PEG-20 Esters (skin conditioning agent/thickener), Cyclopentasiloxane, Trimethylsiloxysilicate (silicone slip agents), Glycerin (skin-repairing ingredient), Caprylyl Methicone (skin conditioning agent), Stearic Acid, Squalane (emollients), Sodium Hyaluronate (skin-repairing ingredient), Tocopherol, Tocopheryl Acetate (vitamin E/antioxidants), Ubiquinone, Glycine Soja (Soybean) Seed Extract, Oryzanol, Leontopodium Alpinum Flower/Leaf Extract, Buddleja Davidii Extract (antioxidants), Aloe Barbadensis Leaf Juice (water-binding agent), Diisopropyl Dimer Dilinoleate (emollient), Dimethicone/Vinyl Dimethicone Crosspolymer (silicone film-forming agent), Cetyl Alcohol, C12-15 Alkyl Benzoate (thickeners), Polyacrylamide (film-forming agent), Polyhydroxystearic Acid (thickener), Isopropyl Titanium Triisostearate/Triethoxycaprylylsilane Crosspolymer (polymer-based texture enhancer), Triethoxycaprylylsilane Crosspolymer (binding agent), Laureth-7 (emulsifier), Thymus Vulgaris Extract (antioxidant), C13-14 Isoparaffin, Alumina (thickeners), Sodium Hydroxide (pH adjuster), Xanthan Gum (thickener), Disodium EDTA (chelating agent), Dehydroacetic Acid, Benzyl Alcohol (preservatives).

My Thoughts
To begin with, I love that this does NOT irritate my eyes. Far too many moisturizers with SPF irritate and burn my eyes – either immediately upon application or within an hour of application. This does not.

I’ve been using this product for about three weeks so far. I love it on its own, and I also like to mix in the Paula’s Choice RESIST Super-Light Daily Defense SPF 30, which is tinted (and took dark for me on its own). I typically mix it 50/50. With a 50/50 mix, it matches my skintone nicely and provides enough coverage for me if my skin is behaving.

I really like the texture of this product. It applies smoothly. Makeup applies nicely on top of it, with or without a primer. It’s moisturizing without being too oily. Between my rosacea meds and working out, my skin has been on the dry side so I needed a moisturizer with SPF with a bit  more moisture in it. This has really been doing the trick.

It has no scent that I can discern. It really is comfortable to wear. I love that it’s filled with antioxidants and that it’s supposed to help even out your skintone. I know it’s supposed to minimize wrinkles and brown spots, as well as help to rebuild collagen. I do feel like my skin looks brighter.

My only complaint is that this is not SPF 50, which I wish was the case. Again, I know it’s just I _feel_ better seeing the higher number, but that the difference between SPF 25 and SPF 50 is quite minimal, especially since I do reapply sunscreen during the day as needed (like if I go outside).

I really like RESIST Cellular Defense Daily Moisturizer SPF 25 and it’s a moisturizer with SPF that I will repurchase.

What do you think of Paula’s Choice RESIST Cellular Defense Daily Moisturizer SPF 25? Would you use it?

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  • Cruelty free
  • Vegan (see Paula’s Choice ingredients page)
  • Fragrance free
  • Great for sensitive skin
  • Moisturizing
  • Anti-aging benefits
  • Good value for the price


  • Only SPF 25